ZONAVAS-50
Composition
Each Film Coated Tablet Contains: - Sacubitril 24mg + Valsartan 26mg
Indication
Sacubitril + Valsartan is a combination medication used primarily in the treatment of heart failure, particularly chronic heart failure, to reduce the risk of hospitalization and death. This innovative drug pairs two active ingredients, Sacubitril and Valsartan, which both work in tandem to improve heart function and overall cardiovascular health.
Sacubitril and Valsartan belong to a class of medications known as Angiotensin Receptor Neprilysin Inhibitors (ARNI). This class of drugs is designed to target two key mechanisms that contribute to heart failure: the overactive renin-angiotensin-aldosterone system (RAAS) and neprilysin. By inhibiting neprilysin, Sacubitril enhances the beneficial effects of natriuretic peptides, which help the heart and blood vessels function more effectively. Valsartan, an angiotensin II receptor blocker (ARB), works by blocking the effects of a hormone that can constrict blood vessels and increase blood pressure, leading to less strain on the heart.
Together, Sacubitril + Valsartan relaxes the blood vessels, improving blood flow and making it easier for the heart to pump blood throughout the body. This alleviates the burden on the heart, particularly in cases of heart failure, where the heart's pumping ability is compromised. Moreover, this combination also reduces the retention of water in the body, helping to prevent fluid buildup and the associated swelling that often occurs in heart failure patients.
Zonavas 50 tablets contain Sacubitril 24mg + Valsartan 26mg, offering an effective treatment option for managing chronic heart failure. This medication helps improve heart function, reduce symptoms, and lower the risk of hospitalization in affected patients. Zonavas 50 tablets provide a reliable therapeutic approach for those seeking consistent support in long-term cardiac care and overall heart health management.
Contraindication
Hypotension (low blood pressure), Dizziness, Cough, Increased potassium level in blood, acute renal failure, Decreased haematocrit level, increased creatinine level in blood.
Storage
Cool & Dry Place
Dosage
As directed by a Medical Practitioner or Physician.
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