Astepraz LS
Indication
Esomeprazole and Levosulpiride are combined in the treatment of gastroesophageal reflux disease (GERD) and peptic ulcer disease, offering a multifaceted approach to managing these conditions. Esomeprazole, a proton pump inhibitor (PPI), works by reducing the amount of acid produced in the stomach. By inhibiting the proton pump (H+/K+ ATPase) in the parietal cells of the stomach lining, esomeprazole effectively decreases gastric acidity, providing relief from symptoms and allowing healing of the esophagus and stomach lining. This action is particularly beneficial in treating GERD, a chronic condition where stomach acid frequently flows back into the esophagus, causing irritation and inflammation.
Levosulpiride, on the other hand, is a prokinetic agent and selective dopamine D2 receptor antagonist. It enhances gastrointestinal motility by increasing the release of acetylcholine, thereby improving the movement of food through the stomach and intestines. This helps in alleviating symptoms such as bloating, nausea, and delayed gastric emptying, which are common in patients with GERD and peptic ulcer disease. Levosulpiride's action on the dopamine receptors also has a mild anti-depressant and anti-anxiety effect, which can be beneficial for patients whose gastrointestinal symptoms are exacerbated by stress or anxiety.
The combination of Esomeprazole and Levosulpiride provides a comprehensive treatment approach: Esomeprazole reduces acid production, thereby protecting the esophageal and gastric lining from acid damage, while Levosulpiride enhances gastrointestinal motility, ensuring efficient digestion and reducing reflux episodes. This synergistic effect not only alleviates the primary symptoms of GERD and peptic ulcer disease but also addresses secondary symptoms such as bloating, nausea, and discomfort, offering a holistic management strategy for these conditions. By combining these two medications, healthcare providers can offer patients a more effective and comprehensive treatment option, improving their quality of life and reducing the risk of complications associated with chronic acid reflux and ulcers.
The product Astepraz LS, which includes Levosulpiride 75mg + Esomeprazole 40mg, is marketed in various forms such as Astepraz LS capsules, enteric coated esomeprazole and levosulpiride SR capsules, and Astepraz LS capsule SR. These formulations ensure optimal delivery and efficacy of the active ingredients. Patients can buy Astepraz LS capsules both offline and online, ensuring easy access to this effective treatment. The Astepraz LS capsules manufacturer, supplier, and exporter ensure the availability and distribution of these capsules worldwide, making it convenient to buy Astepraz LS capsules online.
Contraindication
Nausea, Vomiting, Diarrhoea, Headache, Flatulence, Abdominal pain, dizziness, Joint pain, drowsiness.
Storage
Cool & Dry Place
Dosage
As directed by a Medical Practitioner or Physician.
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