Astepraz DSR
Indication
Esomeprazole + Domperidone is a combination medication used primarily in the treatment of gastroesophageal reflux disease (GERD), commonly known as acid reflux, and functional dyspepsia. GERD is a chronic condition where stomach acid frequently flows back into the esophagus, leading to symptoms such as heartburn, chest pain, and difficulty swallowing. Functional dyspepsia, on the other hand, is characterized by upper abdominal discomfort or pain, bloating, and early satiety without an identifiable cause.
Astepraz DSR is a specific formulation of this combination therapy. Astepraz DSR capsules contain enteric coated Esomeprazole and sustained release Domperidone capsules. Each Astepraz DSR capsule provides Domperidone 30mg + Esomeprazole 40mg, ensuring effective relief from both acid production and gastrointestinal motility issues.
Esomeprazole, a proton pump inhibitor (PPI), works by reducing the production of stomach acid. It does this by blocking the enzyme in the wall of the stomach that produces acid, thereby decreasing the amount of acid in the stomach. This reduction helps in relieving symptoms of acid reflux, promoting healing of the esophagus, and preventing further damage. It is particularly effective in providing long-term relief from the chronic symptoms of GERD.
Domperidone, a prokinetic agent, complements the action of Esomeprazole by enhancing gastrointestinal motility. It works by blocking dopamine receptors, which increases the movement of the stomach and intestines, helping to move food more effectively through the digestive tract. This action aids in alleviating symptoms of functional dyspepsia, such as bloating and early satiety, and also helps in reducing the regurgitation of stomach contents back into the esophagus.
The combination of Esomeprazole and Domperidone in Astepraz DSR capsules thus offers a comprehensive approach to managing GERD and functional dyspepsia. By addressing both acid production and gastrointestinal motility, this combination therapy not only provides symptom relief but also promotes overall digestive health. It is essential, however, for patients to use this medication under the guidance of a healthcare professional to ensure its efficacy and safety, considering the potential side effects and interactions with other medications.
Contraindication
Diarrhoea, Flatulence, Headache, Nausea, Vomiting, Constipation, Fundic gland polyps, abdominal pain.
Storage
Cool & Dry Place
Dosage
As directed by a Medical Practitioner or Physician.
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